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darunavir will enhance the stage or result of cinacalcet by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Individuals with risk components for higher GI bleeding (which include recognized gastritis, esophagitis, ulcers or severe vomiting) might be at increased chance for GI bleeding when receiving Sensipar treatment.
In clients in danger, receiving therapy, who create hypocalcemia, closely monitor corrected serum calcium and QT interval
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The following adverse reactions are recognized throughout postapproval usage of Sensipar. Since these reactions are claimed voluntarily from the populace of uncertain dimensions, It's not always probable to reliably estimate their frequency or build a causal marriage to drug publicity.
eslicarbazepine acetate will lower the level or outcome of cinacalcet by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
dexamethasone will lessen the level or outcome of cinacalcet by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
fosphenytoin will minimize the level or impact of cinacalcet by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
dacomitinib will enhance the amount or impact of cinacalcet by affecting hepatic enzyme CYP2D6 metabolism. Stay away from or Use Alternate Drug. Keep away from use with CYP2D6 substrates where by small increases in concentration with the CYP2D6 substrate may bring about severe or daily life-threatening toxicities.
cinacalcet will enhance the amount or effect of valbenazine by impacting hepatic enzyme CYP2D6 metabolism. Modify Therapy/Watch Closely. Contemplate lowering valbenazine dose determined by tolerability if coadministered with a robust CYP2D6 inhibitor.
When you pass up a dose, take it once you keep in mind. If it is nearly time on your future dose, skip the missed dose and only consider the following dose. Usually do not just take double or excess doses.
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cinacalcet decreases effects of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Warning/Watch. Prevents conversion of codeine to its active metabolite morphine.